The current COVID-19 pandemic has prompted an unprecedented global search for treatments and vaccines. As stated in my previous post, antibodies have attractions as potential antiviral treatments, and trials are already underway using convalescent plasma from patients who have recovered from infection with SARS-CoV-2. I have already mentioned the limitations of this approach, however, and the advantages of using highly specific monoclonal antibodies instead.
The fact that viruses reproduce using the host cells’ metabolic processes makes it more difficult to design drugs to target them after they have entered the cells. There is always the possibility that any drug developed might damage the host as well. It is far better to prevent the virus entering the cells using a chemical entity specifically targeted at the virus in question: this is where antibodies come in.
For years now UK politics has been like this: whatever the Conservative Government says I assume is a lie until proven otherwise. I find this to be a significant source of stress. There are numerous examples of the UK Government lying to the public in the last few years, but perhaps the most outrageous recent examples are the lies they have told over the preparation for, and management of, the current COVID Pandemic.
Zoonoses (human infections of animal origin) have become increasingly important in recent decades. Viral infections in this category include HIV, Ebola, and the Coronavirus diseases MERS, SARS, and most recently COVID-19 caused by SARS-CoV-2. This is not an accident: it results from the relentless tendency of humans to plunder ecosystems without regard for the consequences.
President Donald Trump has made a number of references in the past, and made a few more in his recent 4th July Address to the Nation, to the fact that SARS-CoV-2 originated in China. He always makes these remarks in a way that suggests (a) that China deliberately, or by negligence inflicted the virus on the World; and (b) that such a thing would never happen in the United States of America.
A lot of the strange conspiracy theories connected with COVID involve 5G mobile networks. These ideas have sprung up all over the World, even in countries like Bolivia, which doesn’t have 5G technology!
I previously made the point that social media platforms can provide an invaluable means of spreading useful public health information about the coronavirus crisis. Unfortunately, the pandemic has also generated a variety of bizarre beliefs, and these have spread throughout the World, largely through social media. Social media services have also allowed individuals to denigrate effective measures, such as social distancing, and to promote totally ineffective coronavirus “cures”.
I used to be a great sleeper. As a child, I remember there once was a severe storm that caused a lot of structural damage, including blowing down several chimneys in Glasgow tenements. I slept right through it! None of the stresses and strains of my professional life ever led me to lose much sleep, although, to be fair, until I went part-time in my last 2 years of work, I think exhaustion was a great help in leading me to the Land of Nod!
Covert hairdressing in the Time of COVID One of the most irritating things about Coronavirus Lockdown is not being able to get a haircut. I have a strong family history of baldness, and as I have got older my hair has become pretty thin on top. However, the same can’t be said for the back…
Effects of the novel Coronavirus on multiple systems Based on the experience of SARS, COVID was expected by most people to be a respiratory illness. However, it quickly became apparent that, as well as spreading much more readily than the SARS virus, SARS-CoV-2 was producing a much more complicated illness that affected multiple bodily systems.…